• Users Online: 366
  • Print this page
  • Email this page
REVIEW ARTICLE
Year : 2020  |  Volume : 22  |  Issue : 4  |  Page : 35-44

Potential treatment of COVID-19


1 Pulmonary Diseases Clinic, University of Health Sciences, Sultan Abdulhamit Han Education and Research Hospital, Istanbul, Turkey
2 Pulmonary Diseases Clinic, Yedikule Pulmonary Diseases and Thoracic Surgery Education and Research Hospital, Istanbul, Turkey
3 Pulmonary Diseases Clinic, University of Health Sciences, Süreyyapaşa Pulmonary Diseases and Thoracic Surgery Education and Research Hospital, Istanbul, Turkey
4 Department of Pulmonary Diseases, Başkent University Adana Dr. Turgut Noyan Application and Research Center, Adana, Turkey

Correspondence Address:
Dr. Nazan Şen
Baskent University Adana Dr. Turgut Noyan Application and Research Center, Dadaloglu Mh Serinevler 2591 Sk 4/A Yüregir, Adana
Turkey
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ejop.ejop_61_20

Rights and Permissions

Following the first reported cases of pneumonia of unknown etiology at the end of 2019 in Wuhan city, Hubei province, China, the causative agent was demonstrated to be a new coronavirus that has not been defined in humans before. The World Health Organization (WHO) named this virus as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and the disease caused by the virus as coronavirus disease-19 (COVID-19). The disease spread rapidly to other countries through human-to-human transmission, and WHO declared a pandemic on March 11, 2020. As of April 2020, the number of individuals infected with SARS-CoV-2 and COVID-19 related deaths continue to increase rapidly worldwide. The main reason for the increase in the rate of infection is person-to-person transmission, while the main reason for the increase in mortality rate is the lack of a proven medical treatment specific to COVID-19 and the severe course of the disease in the elderly with low immunity. While a vast majority of individuals infected with SARS-CoV-2 are asymptomatic or recover after displaying mild symptoms, hospitalization is required in 14% of cases and severe disease requiring intensive care admission is seen in 5% of the infected individuals. WHO and national guidelines do not make clear recommendations regarding treatments for symptomatic patients. Currently, there is no vaccine or specific antiviral treatment for COVID-19, however supportive care, isolation and protective measures and experimental drugs/treatments are being used for the management of COVID-19. Medical treatments being used for COVID-19, aim to prevent the entry of the virus into the cell, to inhibit or reduce its replication, and to suppress the increased inflammatory response. In addition, “convalescent” plasma, which includes antibodies of patients who were completely recovered from the infection, is among the treatment options.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed3369    
    Printed39    
    Emailed0    
    PDF Downloaded179    
    Comments [Add]    
    Cited by others 2    

Recommend this journal